Press release

Lack of Sleep and Chronic Stress Hurt the Immune System: Here’s How Vagus Nerve Stimulation Can Help During a Global Pandemic

Sponsored by Businesswire

Stress is a part of life for many of us – especially now more than ever. Whether we are having trouble adjusting to working from home, caring for a sick relative or home-schooling children, it seems everyone is experiencing some form of stress during this global health crisis. However, science tells us that extreme amounts of stress and sleeplessness can suppress our immune system and make us more vulnerable to illnesses.

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When toned or strengthened like a muscle, the functions of the vagus nerve can be amplified – bringing on feelings of calm, boosted mood and better sleep. (Photo: Business Wire)

When toned or strengthened like a muscle, the functions of the vagus nerve can be amplified – bringing on feelings of calm, boosted mood and better sleep. (Photo: Business Wire)

“It’s well established, scientifically, that chronic stress and sleeplessness can significantly blunt the immune system. Right now, Americans are experiencing extraordinary stress at a time when compromised immunity can be devastating,” said Dr. Richard Cartledge, Chief of Cardiovascular Surgery at Boca Raton Regional Hospital and inventor of Xen by Neuvana. “One of the most remarkable ways known to combat your body’s stress response is through electronic vagus nerve stimulation. We created Xen by Neuvana to make this previously inaccessible technology available to everyone.”

People are feeling the effects of stress more than ever

Chronic stress, worry, and lack of sleep negatively impact our immune system, throwing it off balance and increasing the risk for development or worsening of diseases. In these challenging times, people are experiencing new stressors – from job security to taking care of children out of school and adjusting to working from home. In a recent survey by Neuvana, more than half (51%) of Americans said working from home adds to their feelings of stress.

Isolation can take its toll, as well. Social interaction may indirectly strengthen immunity, as friends typically help with encouragement of healthy behaviors and help buffer the stress of negative events. Studies have shown that individuals who are socially isolated are approximately 2-2.5 times more likely to have clinically high levels of C-reactive protein, which measures inflammation as a sign of stress in the body, as opposed to those who are socially well integrated.

The chronic stress we are experiencing these days can have many short- and long-term effects – suppressing immunity, decreasing the number of immune cells and increasing the number of immunosuppressive cells. In the short and medium term, it can create social anxiety, sensitivity to pain, disrupted sleep, chronic pain, depressed mood and social withdrawal. And in the long term, individuals under chronic stress are more likely to experience susceptibility to infection, inflammatory diseases, accelerated aging and early mortality. Cortisol, the body’s primary stress hormone, is produced in abnormally high amounts during chronic stress, which can depress the immune system.

Managing stress and getting enough sleep can help us to fight off illness, to lower the risk of diseases and may even help enhance our response to vaccinations. One way to help boost your immune system, right now, at home, is through vagus nerve stimulation (VNS).

What is Vagus Nerve Stimulation (VNS)?

Your brain and body are designed to “self soothe” during or after stressful moments. Your parasympathetic nervous system kicks in to balance the stress response and promote relaxation by slowing your heart rate and breathing – and the vagus nerve plays a key role in coordinating this response. While stimulation of the vagus nerve has become a more common topic in recent years, humans have practiced forms of vagus nerve stimulation for centuries through meditation, yoga, mindfulness and deep breathing exercises. When toned or strengthened just like a muscle, the functions of the vagus nerve can be amplified – bringing on feelings of calm, boosted mood and better sleep.

Neuvana brings the benefits of VNS home

Neuvana – a team of physicians, expert engineers and wellness practitioners – has found a way to bring the calming effects of VNS through Xen – a new wellness device that safely and gently tones the vagus nerve for better sleep and reduced stress and anxiety.

Xen by Neuvana works by sending a gentle, calming electrical signal via patented earbuds to the part of the vagus nerve located in the ear. This promotes relaxation during any activity – even while social distancing – like working from home, after a yoga session, reading a book to the kids before bed, or listening to music. Regular use delivers maximum benefits, often with just two 15-20-minute sessions a day.

In light of April’s Stress Awareness Month and this global health crisis, the team at Neuvana want to make VNS more accessible and are offering the Xen Box Set for $329, a $70 discount off MSRP through May 15, 2020. Additionally, for every unit sold, Neuvana will donate $20 to Feeding America’s COVID-19 Response Fund. For more promotional information, and other stress relieving and wellness tips, please visit

Xen by Neuvana is available for order today with an optional monthly premium app fee of $3.99. All users will receive a 60-day free trial of the premium app, which includes additional waveforms and signals. Neuvana offers a 30-day money-back guarantee if not fully satisfied.

Media members interested in more information or executive interviews may contact Press kit can be found here. Detailed feature and tech spec list can be found here.

This product is for healthy users interested in potentially improving their general wellness. Individual results may vary. Neuvana offers a 30-day money-back guarantee if not fully satisfied.

About Neuvana LLC.

Neuvana is a South Florida-based brand at the intersection of wellness and technology, continually striving to improve people’s lives through accessible Neuroscience. Founded in 2014 by Dr. Richard Cartledge, an avid inventor and Chief of Cardiovascular Surgery at Boca Raton Regional Hospital, the company is made up of physicians, intellectual property experts, engineers, experienced business professionals and a world-class scientific advisory board with a shared goal: a platform to make the wellness benefits of neuroscience safe, easy and accessible to everyone.